Nanostructural surface development for dental implant manufacturing

The project NanoSurf is targeted to strengthen international and intersectoral collaboration in dental implant research, sharing new ideas and knowledge transfer from research to market and vice versa. We will investigate nanostructured metal oxide coatings, 3D scaffolds, obtained by electrospinning deposition of organic nanofibers and lazer patterning of the implant surface using biotechnology, cell engineering and nanotechnology. Interdisciplinary project research and innovation goals are targeted to develop a new class of dental implants with advanced mechanical properties and improved surfaces, treated with nanotechnological methods which will demonstrate high biocompatibility, antibacterial properties and integration with a patient’s bone. The developed devices will simplify dental surgery and avoid bacterial inflammatory complications after the implant surgery. This can provide better dental services and improve health of EU society.
The project partners will provide research and training activities in the fields of fabrication and characterization of Zirconium-Titanium (ZrTi) alloy-based dental implants, sol-gel deposition of metal oxides, biopolymers and organic/inorganic nanolaminates, laser patterning, electrospinning, structural characterization, cell engineering, modeling analysis and commercialisation of scientific achievements from research results to final product.
Research and management training will be provided to experienced and early stage researchers to strengthen their personal skills, improve their track record and expertise via new scientific papers and conference presentations and strengthen a development of EU research human resources. Long lasting collaboration between partners, based on co-supervising students and preparation of novel collaborative project proposals is foreseen. Dissemination of project results will make an impact on development of EU research potential in the fields of bio-, nanotechnology and applied science.

Objective

MSCA-RISE – Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE)

Deliverables

Recommendation for development of dental implants with optimal mechanical properties

Validation and optimization of parameters will be performed

Methodology of ZrTiNb-based metal alloy preparation

Methodology of ZrTiNb-based metal alloy preparation with tuned properties will be reported.

Prototype of dental implant with advanced mechanical properties

Prototype of dental implant with advanced mechanical properties will be developed

Publications

Chemical and Structural Characterization of Sandlasted Surface of Dental Implant using ZrO2 Particle with Different Shape

Author(s): Oleg Mishchenko, Vira Filatova, Mykhaylo Vasylyev, Volodymyr Deineka, Maksym Pogorielov

Published in: Coatings, Issue 9/4, 2019, Page(s) 223, ISSN 2079-6412

DOI: 10.3390/coatings9040223

Degradation and In Vivo Response of Hydroxyapatite-Coated Mg Alloy

Author(s): Yevheniia Husak, Oleksandr Solodovnyk, Anna Yanovska, Yevhenii Kozik, Iryna Liubchak, Viktoriia Ivchenko, Oleg Mishchenko, Yevhen Zinchenko, Vladimir Kuznetsov, Maksym Pogorielov

Published in: Coatings, Issue 8/11, 2018, Page(s) 375, ISSN 2079-6412

DOI: 10.3390/coatings8110375

Cell and tissue response to nanotextured Ti6Al4V and Zr implants using high-speed femtosecond laser-induced periodic surface structures

Author(s): Iaroslav Gnilitskyi, Maksym Pogorielov, Roman Viter, Ana Maria Ferraria, Ana Patrícia Carapeto, Olexandr Oleshko, Leonardo Orazi, Oleg Mishchenko

Published in: Nanomedicine: Nanotechnology, Biology and Medicine, 2019, Page(s) 102036, ISSN 1549-9634

DOI: 10.1016/j.nano.2019.102036